Crystal structures ofN2,N3,N5,N6-tetrakis(pyridin-2-ylmethyl)pyrazine-2,3,5,6-tetracarboxamide andN2,N3,N5,N6-tetrakis(pyridin-4-ylmethyl)pyrazine-2,3,5,6-tetracarboxamide

C3sc50242b 2349..2356

Polarizability is a key molecular property controlling induction and dispersion forces in molecules, and atomic polarizabilities in molecules are widely used elements both in qualitative schemes for understanding molecular interactions and in quantitative methods for modeling them. Unfortunately, experimental probes of local polarizability are not readily available. Here we predict the polariza...

Notes in Artificial Intelligence 2356

Analgesic, Anticonvulsant and Antiparkinsonian Activities of Some Synthesized 2,6-bis(Tetracarboxamide)-pyridine and Macrocyclic Tripeptide Derivatives

A series of synthesized 2,6-bis(tetracarboxamide)-pyridine and macrocyclic tripeptide derivatives 1-6 were previously prepared and screened as antimicrobial, anti-inflammatory and anticancer agents. The compounds for evaluation of analgesic, anticonvulsant and antiparkinsonian activities were used. Analgesic activities of selected compounds determined by hot plate assay, all tested compounds sh...

Transmitting information along oligo-para-phenylenes: 1,12-stereochemical control in a terphenyl tetracarboxamide.

Amide-substituted terphenyls adopt a well-defined conformation that allows the transmission of stereochemical information from a controlling centre to a reaction site 11 bond lengths away, providing a model of how extended polymeric systems might be used to communicate binary information.

[Frontiers in Bioscience 13, 2356-2363, January 1, 2008] 2356 DP IV/CD26, APN/CD13 and related enzymes as regulators of T cell immunity: implications for experimental encephalomyelitis and multiple sclerosis

1 Institute of Molecular and Clinical Immunology, Otto-von-Guericke University Magdeburg, Germany, 2 IMTM GmbH, Department Immunopharm, Magdeburg, Germany, 3 University Clinic of Dermatology and Venereology, Otto-von-Guericke University Magdeburg, Germany, 4 Institute of Experimental Internal Medicine, Otto-von-Guericke University Magdeburg, Germany, 5 Institute of Biochemistry and Biotechnolog...